Publications

Gut Microbiota Dysbiosis: Triggers, Consequences, Diagnostic and Therapeutic Options

Authors: Authors: Tomas Hrncir

Publisher: Microorganisms, 2022,10,578

Detection of galanin receptors in the spinal cord in experimental autoimmune encephalomyelitis

Authors: Authors: Danica Michalickova, Ivana Kramarikova, Hatice Kubra Ozturk, Tomas Kucera, Tomas Vacik, Tomas Hrncir, Nikolina Kutinova Canova, Martin Sima, Ondrej Slanar

Publisher: Biometric Papers 2022;116

Edaravone attenuates disease severity of experimental auto-immune encephalomyelitis and increases gene expression of Nrf2 and HO-1

Authors: Authors: Michaličková, D.; Öztürk, H.K.; Hroudová, J.; Ľupták, M.; Kučera, T.; Hrnčíř, T.; Šíma, M.; Slanař, O

Publisher: Physiological Research 2022

Gut Microbiota and NAFLD: Pathogenetic Mechanisms, Microbiota Signatures, and Therapeutic Interventions

Authors: Authors: Hrncir, T.; Hrncirova, L.; Kverka, M.; Hromadka, R.; Machova, V.; Trckova, E.; Kostovcikova, K.; Kralickova, P.; Krejsek, J.; Tlaskalova-Hogenova, H.

Publisher: Microorganisms 2021, 9, 957

Severity of Experimental Autoimmune Uveitis Is Reduced by Pretreatment with Live Probiotic Escherichia coli Nissle 1917

Authors: Authors: Dusek O, Fajstova A, Klimova A, Svozilkova P, Hrncir T, Kverka M, Coufal S, Slemin J, Tlaskalova-Hogenova H, Forrester JV, Heissigerova J

Publisher: Cells 2020 Dec 25;10(1):23

Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling.

Authors: Authors: Fajstova A, Galanova N, Coufal S, Malkova J, Kostovcik M, Cermakova M, Pelantova H, Kuzma M, Sediva B, Hudcovic T, Hrncir T, Tlaskalova-Hogenova H, Kverka M, Kostovcikova K

Publisher: Cells. 2020 Dec 16;9(12):2701

Targeting Keap1/Nrf2/ARE signaling pathway in multiple sclerosis

Authors: Authors: Michaličková D, Hrnčíř T, Canová NK, Slanař O

Publisher: Eur J Pharmacol. 2020 Apr 15;873:172973

The role of gut microbiota in intestinal and liver diseases

Authors: Hrncir T, Hrncirova L, Kverka M, Tlaskalova-Hogenova H

Lab Anim 2019, 53: 271

Human gut microbes are susceptible to antimicrobial food additives in vitro

Authors: Hrncirova L, Hudcovic T, Sukova E, Machova V, Trckova E, Krejsek J, Hrncir T

Folia Microbiol (Praha) 2019, 64: 497

Food Preservatives Induce Proteobacteria Dysbiosis in Human-Microbiota Associated Nod2-Deficient Mice

Authors: Hrncirova L, Machova V, Trckova E, Krejsek J, Hrncir T

Microorganisms 2019, 7: 383

Microbiota affects the expression of genes involved in HPA axis regulation and local metabolism of glucocorticoids in chronic psychosocial stress

Authors: Vodicka M, Ergang P, Hrncir T, Mikulecka A, Kvapilova P, Vagnerova K, Sestakova B, Fajstova A, Hermanova P, Hudcovic T, Kozakova H, Pacha J

Brain Behav Immun 2018, 73: 615

Nod2 is required for the regulation of commensal microbiota in the intestine

Authors: Petnicki-Ocwieja T, Hrncir T, Liu Y, J, Biswas A, Hudcovic T, Tlaskalova-Hogenova H, Kobayashi KS

Proc Natl Acad Sci U S A 2009, 106: 15813

The role of gut microbiota (commensal bacteria) and the mucosal barrier in the pathogenesis of inflammatory and autoimmune diseases and cancer: contribution of germ-free and gnotobiotic animal models of human diseases

Authors: Tlaskalová-Hogenová H, Stěpánková R, Kozáková H, Hudcovic T, Vannucci L, Tučková L, Rossmann P, Hrnčíř T, Kverka M, Zákostelská Z, Klimešová K, Přibylová J, Bártová J, Sanchez D, Fundová P, Borovská D, Srůtková D, Zídek Z, Schwarzer M, Drastich P, Funda DP

Cell Mol Immunol 2011, 8: 110

Segmented filamentous bacteria in a defined bacterial cocktail induce intestinal inflammation in SCID mice reconstituted with CD45RBhigh CD4+ T cells

Authors: Stepankova R, Powrie F, Kofronova O, Kozakova H, Hudcovic T, Hrncir T, Uhlig H, Read S, Rehakova Z, Benada O, Heczko P, Strus M, Bland P, Tlaskalova-Hogenova H

Inflamm Bowel Dis 2007, 13: 1202

Gut microbiota and lipopolysaccharide content of the diet influence development of regulatory T cells: studies in germ-free mice

Authors: Hrncir T, Stepankova R, Kozakova H, Hudcovic T, Tlaskalova-Hogenova H

BMC Immunol 2008, 9: 65

Oral administration of Parabacteroides distasonis antigens attenuates experimental murine colitis through modulation of immunity and microbiota composition

Authors: Kverka M, Zakostelska Z, Klimesova K, Sokol D, Hudcovic T, Hrncir T, Rossmann P, Mrazek J, Kopecny J, Verdu E, F, Tlaskalova-Hogenova H

Clin Exp Immunol 2011, 163: 250

Lactocepin secreted by Lactobacillus exerts anti-inflammatory effects by selectively degrading proinflammatory chemokines

Authors: von Schillde M, A, Hörmannsperger G, Weiher M, Alpert C, A, Hahne H, Bäuerl C, van Huynegem K, Steidler L, Hrncir T, Pérez-Martínez G, Kuster B, Haller D

Cell Host Microbe 2012, 11: 387

Involvement of innate immunity in the development of inflammatory and autoimmune diseases

Authors: Tlaskalová-Hogenová H, Tucková L, Stepánková R, Hudcovic T, Palová-Jelínková L, Kozáková H, Rossmann P, Sanchez D, Cinová J, Hrncír T, Kverka M, Frolová L, Uhlig H, Powrie F, Bland P

Ann N Y Acad Sci 2005, 1051: 787

Negative regulation of Toll-like receptor signaling plays an essential role in homeostasis of the intestine

Authors: Biswas A, Wilmanski J, Forsman H, Hrncir T, Hao L, Tlaskalova-Hogenova H, Kobayashi KS

Eur J Immunol 2011, 41: 182

Altered gut microbiota promotes colitis-associated cancer in IL-1 receptor-associated kinase M-deficient mice

Authors: Klimesova K, Kverka M, Zakostelska Z, Hudcovic T, Hrncir T, Stepankova R, Rossmann P, Ridl J, Kostovcik M, Mrazek J, Kopecny J, Kobayashi K, S, Tlaskalova-Hogenova H

Inflamm Bowel Dis 2013, 19: 1266