Publications

Early infection-induced natural antibody response.

Authors: Kubelkova K, Hudcovic T, Kozakova H, Pejchal J, Macela A.

Sci Rep. 2021,1541.

Secretory IgA N-glycans contribute to the protection against E. coli O55 infection of germ-free piglets.

Authors: Raskova Kafkova L, Brokesova D, Krupka M, Stehlikova Z, Dvorak J, Coufal S, Fajstova A, Srutkova D, Stepanova K, Hermanova P, Stepankova R, Uberall I, Skarda J, Novak Z, Vannucci L, Tlaskalova-Hogenova H, Jiraskova Zakostelska Z, Sinkora M, Mestecky J, Raska M.

Mucosal Immunol. 2021, 511.

The role of the microbiome and psychosocial stress in the expression and activity of drug metabolizing enzymes in mice.

Authors: Zemanová N, Anzenbacher P, Zapletalová I, Jourová L, Hermanová P, Hudcovic T, Kozáková H, Vodička M, Pácha J, Anzenbacherová E.

Sci Rep. 2020, 8529.

Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling.

Authors: Fajstova A, Galanova N, Coufal S, Malkova J, Kostovcik M, Cermakova M, Pelantova H, Kuzma M, Sediva B, Hudcovic T, Hrncir T, Tlaskalova-Hogenova H, Kverka M, Kostovcikova K.

Cells. 2020, 2701.

Gut Microbiome Alters the Activity of Liver Cytochromes P450 in Mice With Sex-Dependent Differences.

Authors: Jourova L, Vavreckova M, Zemanova N, Anzenbacher P, Langova K, Hermanova P, Hudcovic T, Anzenbacherova E:

Front. Pharmacol. 2020, 01303.

Presence or Absence of Microbiome Modulates the Response of Mice Organism to Administered Drug Nabumetone.

Authors: Jourová L, Lišková B, Lněničková K, Zemanová N, Anzenbacher P, Hermanová PP, Hudcovic T, Kozáková H, Anzenbacherová E.

Physiol. Res. 69 (Suppl. 4): S000-S000, 2020

Interactions Between Gut Microbiota and Acute Restraint Stress in Peripheral Structures of the Hypothalamic-Pituitary-Adrenal Axis and the Intestine of Male Mice.

Authors: Vagnerová K, Vodička M, Hermanová P, Ergang P, Šrůtková D, Klusoňová P, Balounová K, Hudcovic T, Pácha J

Front Immunol. 2019 Nov 19;10:2655

Optimal Tolerogenic Dendritic Cells in Type 1 Diabetes (T1D) Therapy: What Can We Learn From Non-obese Diabetic (NOD) Mouse Models

Authors: Funda DP, Palová-Jelínková L, Goliáš J, Kroulíková Z, Fajstová A, Hudcovic T, Špíšek R

Front Immunol. 2019 May 14;10:967

Diet Rich in Animal Protein Promotes Pro-inflammatory Macrophage Response and Exacerbates Colitis in Mice

Authors: Kostovcikova K, Coufal S, Galanova N, Fajstova A, Hudcovic T, Kostovcik M, Prochazkova P, Jiraskova Zakostelska Z, Cermakova M, Sediva B, Kuzma M, Tlaskalova-Hogenova H, Kverka M

Front Immunol. 2019 Apr 26;10:919

Germ-Free Mice Exhibit Mast Cells With Impaired Functionality and Gut Homing and Do Not Develop Food Allergy.

Authors: Schwarzer M, Hermanova P, Srutkova D, Golias J, Hudcovic T, Zwicker C, Sinkora M, Akgün J, Wiedermann U, Tuckova L, Kozakova H, Schabussova I.

Front Immunol. 2019 Feb 12;10:205

Gut microbiota metabolizes nabumetone in vitro: Consequences for its bioavailability in vivo in the rodents with altered gut microbiome.

Authors: Jourova L, Anzenbacher P, Matuskova Z, Vecera R, Strojil J, Kolar M, Nobilis M, Hermanova P, Hudcovic T, Kozakova H, Kverka M, Anzenbacherova E

Xenobiotica. 2019 Nov;49(11):1296-1302

Microbiota affects the expression of genes involved in HPA axis regulation and local metabolism of glucocorticoids in chronic psychosocial stress

Authors: Vodička M, Ergang P, Hrnčíř T, Mikulecká A, Kvapilová P, Vagnerová K, Šestáková B, Fajstová A, Hermanová P, Hudcovic T, Kozáková H, Pácha J

Brain Behav Immun. 2018 Oct;73:615-624

Colonization by non-pathogenic bacteria alters mRNA expression of cytochromes P450 in originally germ-free mice

Authors: Jourová L, Anzenbacher P, Lišková B, Matušková Z, Hermanová P, Hudcovic T, Kozáková H, Hrnčířová L, Anzenbacherová E

Folia Microbiol (Praha). 2017 Nov;62(6):463-469

Assessment of the synbiotic properites of human milk oligosaccharides and Bifidobacterium longum subsp. infantis in vitro and in humanised mice

Authors: Musilova S, Modrackova N, Hermanova P, Hudcovic T, Svejstil R, Rada V, Tejnecky V, Bunesova V

Benef Microbes. 2017 Apr 26;8(2):281-289

Chemical characterization and immunomodulatory properties of polysaccharides isolated from probiotic Lactobacillus casei LOCK 0919

Authors: Górska S, Hermanova P, Ciekot J, Schwarzer M, Srutkova D, Brzozowska E, Kozakova H, Gamian A

Glycobiology. 2017 Mar 15;27(3):275-277

Polysaccharides L900/2 and L900/3 isolated from Lactobacillus rhamnosus LOCK 0900 modulate allergic sensitization to ovalbumin in a mouse model

Authors: Górska S, Schwarzer M, Srutkova D, Hermanova P, Brzozowska E, Kozakova H, Gamian A

Microb Biotechnol. 2017 May;10(3):586-593

Colonization of germ-free mice with a mixture of three lactobacillus strains enhances the integrity of gut mucosa and ameliorates allergic sensitization

Authors: Kozakova H, Schwarzer M, Tuckova L, Srutkova D, Czarnowska E, Rosiak I, Hudcovic T, Schabussova I, Hermanova P, Zakostelska Z, Aleksandrzak-Piekarczyk T, Koryszewska-Baginska A, Tlaskalova-Hogenova H, Cukrowska B

Cell Mol Immunol. 2016 Mar;13(2):251-62

Microbiota affects the expression of genes involved in HPA axis regulation and local metabolism of glucocorticoids in chronic psychosocial stress

Authors: Vodička M, Ergang P, Hrnčíř T, Mikulecká A, Kvapilová P, Vagnerová K, Šestáková B, Fajstová A, Hermanová P, Hudcovic T, Kozáková H, Pácha J

Brain Behav Immun. 2018 Oct;73:615-624

Antigen Loading (e.g., Glutamic Acid Decarboxylase 65) of Tolerogenic DCs (tolDCs) Reduces Their Capacity to Prevent Diabetes in the Non-Obese Diabetes (NOD)-Severe Combined Immunodeficiency Model of Adoptive Cotransfer of Diabetes As Well As in NOD Mice

Authors: Funda DP, Goliáš J, Hudcovic T, Kozáková H, Špíšek R, Palová-Jelínková L

Front Immunol. 2018 Feb 16; 9:290

Colonization by nonpathogenic bacteria alters mRNA expression of cytochromes P450 in originally germ-free mice

Authors: Jourová L., Anzenbacher P., Lišková B., Matušková Z., Hermanová P., Hudcovic T., Kozáková H., Hrnčířová L.,Anzenbacherová E.

Folia Microbiol. 2017 Nov, Volume: 62 Issue: 6 Pages: 463-469

Synbiotic properties of human milk oligosaccharides and Bifidobacterium longum subsp. infantis in vitro and in humanized mice

Authors: Musilova S., Modrackova N., Hermanova P., Hudcovic T., Svejstil R., Rada V., Tejnecky V. Bunesova V.

Benef Microbes. 2017 Jan 24; 1-9

Polysaccharides L900/2 and L900/3 isolated from Lactobacillus rhamnosus LOCK 0900 modulate allergic sensitization to ovalbumin in a mouse model

Authors: Górska S, Schwarzer M, Srutkova D, Hermanova P, Brzozowska E, Kozakova H, Gamian A

Microb Biotechnol. 2017 Feb 6

Intestinal microbiota promotes psoriasis-like skin inflammation by enhancing Th17 response

Authors: Zákostelská Z., Málková J., Klimešová K., Rossmann P., Hornová M., Novosádová I., Stehlíková Z., Kostovčík M.,Hudcovic T., Štepánková R., Jůzlová K., Hercogová J., Tlaskalová-Hogenová H., Kverka M.

PLoS One. 2016 Jul 19; 11(7):e0159539

Chemical characterization and immunomodulatory properties of polysaccharides isolated from probiotic Lactobacillus casei LOCK 0919

Authors: Gorska S, Hermanova P, Ciekot J, Schwarzer M, Srutkova D, Brzozowska E, Kozakova H, Gamian A

Glycobiology. 2016 Sep; 26(9):1014-1024

Colonization of germ-free mice with a mixture of three lactobacillus strains enhances the integrity of gut mucosa and ameliorates allergic sensitization

Authors: Kozakova H, Schwarzer M, Tuckova L, Srutkova D, Czarnowska E, Rosiak I, Hudcovic T, Schabussova I, Hermanova P, Zakostelska Z, Aleksandrzak-Piekarczyk T, Koryszewska-Baginska A, Tlaskalova-Hogenova H,Cukrowska B

Cell Mol Immunol. 2016 Mar; 13(2):251-62

Lactobacillus plantarum strain maintains growth of infant mice during chronic undernutrition

Authors: Schwarzer M., Makki K., Storelli G., Machuca-Gayet I., Šrůtková D., Hermanová P., Martino M.E., Balmand S.,Hudcovic T., Heddi A., Rieusset J., Kozáková H., Vidal H., Leulier F.

Science 351 (6275): 854-857, 2016

Development of gut inflammation in mice colonized with mucosa-associated bacteria from patients with ulcerative colitis

Authors: Du Z., Hudcovic T., Mrazek J., Kozakova H., Srutkova D., Schwarzer M., Tlaskalova-Hogenova H., Kostovcik M., Kverka M.

GUT PATHOGENS 7: 32, 2015.

Faecalibacterium prausnitzii Strain HTF-F and Its Extracellular Polymeric Matrix Attenuate Clinical Parameters in DSS-Induced Colitis

Authors: Rossi O., Khan M.T., Schwarzer M., Hudcovic T., Srutkova D., Duncan S. H., Stolte E. H., Kozakova H., Flint H. J., Samson J. N., Harmsen H. J. M., Wells J. M.

PLoS ONE 10: 4, 2015

Neonatal colonization of germ-free mice with Bifidobacterium longum prevents allergic sensitization to major birch pollen allergen Bet v 1

Authors: Schwarzer M., Šrůtková D., Schabussova I., Hudcovic T., Akgün J., Wiedermann U., Kozáková H.

Vaccine 31: 5405-5412, 2013

Authors: