Group leader: Tomáš Hudcovic, PhD. (

Our research group is focused on the study of dysbiosis in the gut microbiota which is connected with the development of the intestinal inflammation. This issue is studied using gnotobiotic mice model of experimental colitis which is induced by treatment with dextran sulfate sodium (DSS). We study the effect of pathogenic and/or probiotic E. coli strains on the development of acute inflammation induced by DSS.