Grants

Current Projects

COST Action FA1401: European network on the factors affecting the gastro-intestinal microbial balance and the impact on the health status of pigs (PiGutNet)

Principal Investigator: P. Trevisi, Co-Investigator: I.Splichal

EU, 2014-2018

A modification of a gut microbiota as a prevention of enteric diseases in newborns: a study in piglet gnotobiotic model, COST-LD

Principal Investigator: I. Splichal

Ministry of Education, Youth and Sports of the Czech Republic

Past Projects

Commensal and probiotic bacteria in prevention of enteric infections in early postnatal period

Principal Investigator: I. Splichal, Co-Investigator: V. Rada

Czech Science Foundation, 2013-2017

Benefits and risks of probiotics for immunocompromised newborns: a study in experimental models

Principal Investigator: A. Splichalova

Czech Science Foundation, 2013-2015

Production of recombinant DNA-binding protein HMGB1 for diagnostic purposes

Principal Investigator: V. Vejvoda, Co-Investigator: I. Splichal

Ministry of industry and trade of the Czech Republic, 2012-2014

Interplay of microbiota and gut function in the developing pig – Innovative avenues towards sustainable animal production

Principal Investigator: H. Smidt, Co-Investigator: I. Splichal

7th FRP, EC, 2009-2013

Antimicrobial peptides and Toll-like receptors in ontogeny and bacterial infections

Principal Investigator: I. Splichal

Czech Science Foundation, 2009-2013

Induction of antimicrobial peptides in Salmonella-caused gastroenteritis in dependence on type lipopolysaccharide

Principal Investigator: I. Splichal

Ministry of Education, Youth and Sports of the Czech Republic, 2007-2011

Modulation of innate immune response by probiotic bacteria

Principal Investigator: I. Splichal, Co-Investigator: V. Rada

Czech Science Foundation, 2007-2011

The role of EPEC virulence factors in inflammatory response of gnotobiotic pigs

Principal Investigator: I. Splichal

Czech Science Foundation, 2005-2007

The role of cytokines in protection effect of live vaccinal strains of Salmonella

Principal Investigator: I. Trebichavsky

Czech Science Foundation, 2005-2007

Research on natural immunity of fetal lungs in pig and laboratory animal models

Principal Investigator: I. Splichal

Ministry of Education, Youth and Sports of the Czech Republic, 2002-2004

Ontogeny of interleukin 18 production in pig and its role in bacterial infection

Principal Investigator: I. Splichal

Czech Science Foundation, 2002-2004