Colonization of germ-free piglets with commensal Lactobacillus amylovorus, Lactobacillus mucosae, and probiotic E. coli Nissle 1917 and their interference with Salmonella Typhimurium.

Authors: Splichal I, Donovan SM, Splichalova Z, Neuzil Bunesova V, Vlkova E, Jenistova V, Killer J, Svejstil R, Skrivanova E, Splichalova A

Publisher: Microorganisms 2019, 7

High mobility group box 1 and TLR4 signaling pathway in gnotobiotic piglets colonized/infected with L. amylovorus, L. mucosae, E. coli Nissle 1917 and S. Typhimurium.

Authors: Splichal I, Donovan SM, Jenistova V, Splichalova I, Salmonova H, Vlkova E, Neuzil Bunesova V, Sinkora M, Killer J, Skrivanova E, Splichalova A

Publisher: Int J Mol Sci 2019, 20

Impact of the lipopolysaccharide chemotype of Salmonella enterica serovar Typhimurium on virulence in gnotobiotic piglets.

Authors: Splichalova A, Splichalova Z, Karasova D, Rychlik I, Trevisi P, Sinkora M, Splichal I

Publisher: Toxins (Basel) 2019, 11

Colonization of preterm gnotobiotic piglets with probiotic Lactobacillus rhamnosus GG and its interference with Salmonella Typhimurium.

Authors: Splichalova A, Jenistova V, Splichalova Z, Splichal I

Publisher: Clin Exp Immunol 2019, 195: 381


Experimental enteric bacterial infections in pigs.

Authors: Splichal I and Splichalova A

Publisher: J Infect Dis 2018, 218: 504

Preterm life in sterile conditions: A study on preterm, germ-free piglets.

Authors: Splichalova A, Slavikova V, Splichalova Z, Splichal I

Publisher: Front Immunol 2018, 9: 220

Selected papers before 2018

Comparison of inflammatory response to transgastric and transcolonic NOTES.

Authors: Hucl T, Benes M, Kocik M, Splichalova A, Maluskova J, Krak M, Lanska V, Heczkova M, Kieslichova E, Oliverius M, Spicak J

Publisher: Gastroenterol Res Pract 2016:7320275, 2016

A modified MacConkey agar for selective enumeration of necrotoxigenic E. coli O55 and probiotic E. coli Nissle 1917.

Authors: Splichalova A, Splichal I, Sonnenborn U, Rada V

Publisher: J Microbiol Methods 104:82-86, 2014

The effect of immunosuppression on manifestations of sepsis in an animal model of cecal ligation and puncture.

Authors: Kieslichova E, Rocen M, Merta D, Kudla M, Splichal I, Cap J, Viklicky O, Gurlich R

Publisher: Transplant Proc 45:770-777, 2013

Development of allele-specific primer PCR for a swine TLR2 SNP and comparison of the frequency among several pig breeds of Japan and the Czech Republic.

Authors: Muneta Y, Minagawa Y, Kusumoto M, Shinkai H, Uenishi H, Splichal I

Publisher: J Vet Med Sci 74:553-559, 2012

Growth of bifidobacteria and clostridia on human and cow milk saccharides.

Authors: Rockova S, Rada V, Marsik P, Vlkova E, Bunesova V, Sklenar J, Splichal I

Publisher: Anaerobe 17:223-225, 2011

Interference of Bifidobacterium choerinum or Escherichia coli Nissle 1917 with Salmonella Typhimurium in gnotobiotic piglets correlates with cytokine patterns in blood and intestine.

Authors: Splichalova A, Trebichavsky I, Rada V, Vlkova E, Sonnenborn U, Splichal I

Publisher: Clin Exp Immunol 163:242-249, 2011

Alarmin HMGB1 is released in the small intestine of gnotobiotic piglets infected with enteric pathogens and its level in plasma reflects severity of sepsis.

Authors: Splichalova A, Splichal I, Chmelarova P, Trebichavsky I

Publisher: J Clin Immunol 31:488-497, 2011

Susceptibility of bifidobacteria to lysozyme as a possible selection criterion for probiotic bifidobacterial strains.

Authors: Rada V, Splichal I, Rockova S, Grmanova M, Vlkova E

Publisher: Biotechnol Lett 32:451-455, 2010

Modulation of natural immunity in the gut by Escherichia coli strain Nissle 1917.

Authors: Trebichavsky I, Splichal I, Rada V, Splichalova A

Publisher: Nutr Rev 68:459-464, 2010

The piglet as a model for B cell and immune system development.

Authors: Butler JE, Lager KM, Splichal I, Francis D, Kacskovics I, Sinkora M, Wertz N, Sun J, Zhao Y, Brown WR, DeWald R, Dierks S, Muyldermans S, Lunney JK, McCray PB, Rogers CS, Welsh MJ, Navarro P, Klobasa F, Habe F, Ramsoondar J

Publisher: Vet Immunol Immunopathol 128:147-170, 2009

Cross-talk of human gut with bifidobacteria.

Authors: Trebichavsky I, Rada V, Splichalova A, Splichal I

Publisher: Nutr Rev 67:77-82, 2009

Susceptibility of germ-free pigs to challenge with protease mutants of Salmonella enterica serovar Typhimurium.

Authors: Splichal I, Rychlik I, Gregorova D, Sebkova A, Trebichavsky I, Splichalova A, Muneta Y, Mori Y

Publisher: Immunobiology 212:577-582, 2007

Attenuated aroA Salmonella enterica serovar Typhimurium does not induce inflammatory response and early protection of gnotobiotic pigs against parental virulent LT2 strain.

Authors: Trebichavsky I, Splichalova A, Rychlik I, Hojna H, Muneta Y, Mori Y, Splichal I

Publisher: Vaccine 24:4285-4289, 2006

The effect of intestinal colonization of germ-free pigs with Escherichia coli on calprotectin levels in plasma, intestinal and bronchoalveolar lavages.

Authors: Splichal I, Fagerhol MK, Trebichavsky I, Splichalova A, Schulze J

Publisher: Immunobiology 209:681-687, 2005

Effect of bacterial virulence on IL-18 expression in the amnion infected with Escherichia coli.

Authors: Splichalova A, Trebichavsky I, Muneta Y, Mori Y, Splichal I

Publisher: Am J Reprod Immunol 53:255-260, 2005

Early cytokine response of gnotobiotic piglets to Salmonella enterica serotype typhimurium.

Authors: Splichal I, Trebichavsky I, Muneta Y, Mori Y

Publisher: Vet Res 33:291-297, 2002